HY-GLOWSERA MSH / Nonapeptide-1

HY-GLOWSERA MSH by HY-Tech Products & Co – Personal Care Ingredients Specialist, South Korea.

Clinical Brightening With Precision. An advanced biomimetic vitamin peptide that delivers powerful skin-brightening results by targeting the melanin production and restores even tone with a triple action approach — anti-inflammation, Plasminogen inhibition, MSH-tyrosinase inhibition, and anti-oxidant effect.

Product Name: HY-GLOWSERA MSH
INCI Name: Tranexamoyl Dipeptide-23, Nonapeptide-1, Glutathione Oxidized
Manufacturer: HY-Tech Products & Co, Seoul, South Korea
Appearance: Colorless Transparent Liquid
Solubility: Water-Soluble
pH: 3.8 (Range: 3.0–6.0)

Key Features:

• Triple action brightening: Anti-inflammation + Plasminogen inhibition + MSH-tyrosinase inhibition
• Advanced biomimetic vitamin peptide complex
• Targets melanin production at multiple pathways
• Restores even skin tone with clinical precision
• Powerful antioxidant effect via Glutathione Oxidized
• Nonapeptide-1 (MSH inhibitor) for targeted depigmentation
• Colorless transparent liquid – easy to formulate
• Microbiologically clean – COA confirmed

Functions:

• Skin Brightening Agent
• MSH-Tyrosinase Inhibitor
• Plasminogen Inhibitor
• Anti-Inflammatory Agent
• Antioxidant
• Melanin Synthesis Inhibitor

Applications:

• Skin Care: Clinical Brightening Serums, Ampoules, Essence, Toners
• Anti-Pigmentation: Dark Spot Treatments, Melasma Formulations, Even Tone Creams
• Anti-Aging: Brightening Eye Creams, Luminosity Boosters
• Complexion Care: BB/CC Creams, Brightening Moisturizers

Recommended Usage Rate:

• Serums / Ampoules / Essence: 2–5%
• Toners / Lightweight Formulas: 1–3%
• Eye Creams / Spot Treatments: 2–5%
• Brightening Moisturizers / BB Creams: 1–3%

General Rule: Start at 1% and increase up to 5% based on desired efficacy and skin tolerance.

How to Use / Formulation Instructions:

1. Weigh out the required amount of HY-GLOWSERA MSH (1–5% of total formula weight)
2. Add to the water phase of your formulation
3. If adding post-emulsification, ensure temperature is below 40°C before incorporation
4. Mix gently until fully dispersed — avoid high shear mixing
5. Adjust final formulation pH to 3.0–6.0 for optimal stability and efficacy
6. Perform compatibility testing before full-scale production

Ingredient Synergies:

• Niacinamide (2–5%) — synergistic brightening + pore-minimizing
• Alpha Arbutin — enhanced tyrosinase inhibition across multiple pathways
• Vitamin C derivatives (e.g., Ascorbyl Glucoside) — boosted antioxidant brightening
• Tranexamic Acid — comprehensive anti-melasma formulations
• Hyaluronic Acid — hydrating + brightening dual-action serums
• Azelaic Acid — anti-inflammatory + depigmentation synergy

Certificate of Analysis (COA) – Results:

• Appearance: Colorless Transparent Liquid – CONFORM
• pH: 3.0–6.0 → Result: 3.8
• Peptide Content – A. Tranexamoyl Dipeptide-23: CONFORM
• Peptide Content – B. Nonapeptide-1: CONFORM
• Peptide Content – C. Glutathione Oxidized: CONFORM
• Microbial – Aerobic Bacterial Count: NMT 1000 CFU/ml → Result: <10 CFU/ml
• Microbial – Total Molds & Yeast Count: NMT 100 CFU/ml → Result: <10 CFU/ml

Conclusion: PASS ✓

Storage & Handling:

• Store in a cool, dry place away from direct sunlight
• Keep container tightly closed when not in use
• Recommended storage temperature: 4–25°C

Frequently Asked Questions (FAQ):

Q: What is HY-GLOWSERA MSH?
A: HY-GLOWSERA MSH is an advanced clinical brightening peptide complex by HY-Tech Products & Co, South Korea. It combines Tranexamoyl Dipeptide-23, Nonapeptide-1, and Glutathione Oxidized for triple-action melanin inhibition and skin brightening.

Q: What is the INCI name?
A: INCI Name: Tranexamoyl Dipeptide-23, Nonapeptide-1, Glutathione Oxidized

Q: How does HY-GLOWSERA MSH work?
A: It works through three simultaneous mechanisms — inhibiting MSH-tyrosinase activity (Nonapeptide-1), blocking plasminogen pathways (Tranexamoyl Dipeptide-23), and providing antioxidant protection (Glutathione Oxidized) — for comprehensive, clinical-grade brightening.

Q: What skin concerns does it address?
A: Hyperpigmentation, melasma, dark spots, uneven skin tone, dullness, and oxidative stress-induced discoloration.

Q: What is the recommended usage rate?
A: 1–5% in formulations. Serums/Ampoules: 2–5%, Toners/Lightweight: 1–3%. Start low and adjust based on efficacy and tolerance.

Q: What does it look like?
A: Colorless transparent liquid – COA confirmed CONFORM.

Q: What is the pH?
A: pH 3.8 (within specification range of 3.0–6.0).

Q: Is it water-soluble?
A: Yes, HY-GLOWSERA MSH is water-soluble. Add to the water phase or post-cool down below 40°C.

Q: What is Nonapeptide-1?
A: Nonapeptide-1 is a biomimetic peptide that inhibits MSH (Melanocyte Stimulating Hormone) receptor activity, directly reducing melanin synthesis for targeted depigmentation.

Q: Is a Certificate of Analysis (COA) available?
A: Yes, COA is available upon request.

Q: How should it be stored?
A: Store in a cool, dry place (4–25°C) away from direct sunlight. Keep container tightly closed when not in use.

Q: Is this product vegan?
A: Yes, HY-GLOWSERA MSH peptides are synthetically derived and suitable for vegan formulations.

COA available upon request. For professional cosmetic formulation use only.